Реферат: The Helicobacter pylori infection diagnosis

3.Citologic method should not be used for eradicating.

Screening and other methods allowing to reduce the cost of the Helicobacter pylori infection diagnosis

For screening they usually use methods based on identificationof specific anti-Helicobacter antibodies class A and G in plasma serum or in capillary blood of investigated patients.

1.Immunoenzyme analysis

2.Express-tests based on immunoprecipitation or immunocitochemie using patients' capillary blood as a test and colour potentiating reaction products.

Express-tests could be used for making cheaper the process of primary diagnosis of the Helicobacter infection, as positive test result allows toexclude expensive equipmentand using methods of direct diagnosis. Express-tests can't be used for identifying eradication after treatment.

The Helicobacter pylori infection therapy

Indications to the Helicobacter pylori infection t herapy

As Russian and foreign scientific and clinical experience showed, gastric and peptic ulcer diseases associated by Helicobacter pylori is an indication to anti-Helicobacter therapy both in the period of acute condition and in the period of remission.

Therapy principles

The basic pronciple of therapy is using combined (3-component) therapy:

· enable to eradicate the Helicobacter pylori bacterium min in 80% cases during the investigations conducted under control;

· which has no noticable side effects thtat cause to stop using the medicines in more than 5% of cases;

· effective if the course duration is 7-14 weeks.

Schemes of treatment

· One-week 3-component therapy using H+-K+-AT Phase blockers standard dose2 times daily (foe example, omeprasol 20 mg 2 times daily, or pantaprasol 40 mg 2 times daily, or lansoprasol 30 mg 2 times daily) along with:

· metronodasol 400 mg 3 times daily (or tinidasol 500 mg 2 times daily) + claritromicin 250 mg 2 times daily

OR

· amoxicillin 1000 mg 2 times daily + claritromicin 500 mg 2 times daily

OR

· amoxicillin 500 mg 3 times daily + metronidasol 400 mg 3 times daily

· One-week 3-component therapy with bismuth:

bismush (colloid substrate bismuth, or gallat bismuth or subsalicilate bismuth) 120 mg 4 times daily along with

tetraciclin 500 mg 4 times daily + metronodasol 250 mg 4 times daily or tinidasol 500 mg 2 times daily

· One-week "quadro"-therapy which makes enable to eradicate Helicobacter pylori strains resistant to the action of well-known antibiotics.

H+-K+-AT Phase blockers standard dose 2 times daily (for example, omeprasol 20 mg 2 times daily, or pantoprasol 40 mg 2 times daily, or lansoprasol 30 mg 2 times daily) along with

bismuth (colloid substrate bismuth, or gallat bismuth or subsalicilate bismuth) 120 mg 4 times daily along with